Memory causes pain, drug controls it

Treatments, Rehabilitation, and Recovery
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Christopher
Posts: 845
Joined: Wed Jun 18, 2003 10:09 pm
Injury Description, Date, extent, surgical intervention etc: Date of Injury: 12/15/02

Level of Injury:
-dominant side C5, C6, & C7 avulsed. C8 & T1 stretched & crushed

BPI Related Surgeries:
-2 Intercostal nerves grafted to Biceps muscle,
-Free-Gracilis muscle transfer to Biceps Region innervated with 2 Intercostal nerves grafts.
-2 Sural nerves harvested from both Calves for nerve grafting.
-Partial Ulnar nerve grafted to Long Triceps.
-Uninjured C7 Hemi-Contralateral cross-over to Deltoid muscle.
-Wrist flexor tendon transfer to middle, ring, & pinky finger extensors.

Surgical medical facility:
Brachial Plexus Clinic at The Mayo Clinic, Rochester MN
(all surgeries successful)

"Do what you can, with what you have, where you are."
~Theodore Roosevelt
Location: Los Angeles, California USA

Memory causes pain, drug controls it

Post by Christopher »

Anyone ever heard of this drug for phobias, Seromycin (D-Cycloserine)?

I'd give it a go if it's been on the market for a while.
I'm phobic of neuropathic pain for sure!

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http://www.sciencedaily.com/upi/index.p ... s-pain.xml
Memory causes pain, drug controls it

EVANSTON, Ill., June 4 (UPI) -- U.S. medical scientists believe they have discovered why people often suffer from life-altering chronic pain long after an injury has healed.

Northwestern University Professor Vania Apkarian said the key source of chronic pain appears to be an old memory trace that essentially gets stuck in the brain's prefrontal cortex -- the site of emotion and learning -- where the brain seems to remember the injury as if it were fresh and can't forget it.

Apkarian, a professor of physiology and anesthesiology at Northwestern's Feinberg School of Medicine, has identified a drug that controls persistent nerve pain by targeting the prefrontal cortex.

The drug is D-Cycloserine, which has been used to treat phobic behavior. In studies, D-Cycloserine appeared to significantly diminish the emotional suffering from pain as well as the sensitivity of the formerly injured site. It also controlled nerve pain resulting from chemotherapy.

The drug -- sold by Eli Lilly under the brand name Seromycin -- has long-term benefits, with animals apparently pain free 30 days after the last dose of a 30-day regime.

The study is to be published this fall in the journal Pain.








Longer and more detailed article on same study...

http://www.biologynews.net/archives/200 ... _pain.html
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